Microsoft PowerPoint - poster_collagen_hemostatic_cpc2012_v120105

Physiological wound healing is a highly regulated process, which can be divided in the three stages of hemostasis, inflammation, and repair. Hemostasis with fibrin formation contributes to the formation of a protective wound scab. This facilitates the following steps by providing a matrix within which cell migration and angiogenesis can take place. Wound dressings consisting of oxidized regenerated cellulose or collagen are often used in treatment of surgical wounds as well as chronic wound care. These biomaterials offer interesting properties such as being absorbable and possessing hemostatic effects. A comprehensive in vitro study was performed to compare the hemostatic properties of wound dressings consisting of collagen and/or oxidized regenerated cellulose.